Dr. Andrea Gropman is a pediatric neurogeneticist. She received her M.D. from the University of Massachusetts School of Medicine, completed a residency in Pediatrics at Johns Hopkins Hospital in Baltimore, MD and subsequent fellowships in neurology/child neurology at George Washington University and Children’s National Hospital, Washington, D.C., clinical and biochemical genetics at the National Institutes of Health, and a mini fellowship in neuroimaging and magnetic resonance spectroscopy at the Huntington Medical Research Institute in Pasadena, CA. She is board certified in neurology/child neurology, genetics, biochemical genetics and neurodevelopmental disabilities. She served as Professor of Pediatrics, Neurology, Genomics and Personalized Medicine at George Washington University for the past 25 years, and served as the division chief for Neurogenetics and Neurodevelopmental disabilities from 2014-2024 and the interim director of genetic medicine research from July 2023-September 2024. Dr. Gropman also is the PI for the Urea Cycle Rare Disorders Consortium and serves leadership roles on the RDCRN and in genetic, metabolic and neurology societies. She is currently the Director of Neurometabolic Translational Research, in the center for experimental therapeutics at St. Jude Childre’s Research Hospital. She has published over 280 articles and reviews and contributed chapters to classic textbooks in genetics and neurology is one of the editors of the classic textbook, Swaiman’s Pediatric Neurology. Dr. Gropman is co author of the textbook, X and Y chromosome Variations. Dr. Gropman's research has focused on several areas including inborn errors of metabolism, in which she is considered an international authority on neuroimaging and brain biomarkers in urea cycle disorders, mitochondrial epigenomics, and chromosome disorders including Smith Magenis syndrome and X and Y chromosome disorders. Dr. Gropman has dedicated her career to the care of children and adults with rare disease. Her talk will focus on her imaging work for urea cycle disorders and impact on understanding the clinical phenotypes.